Effectiveness and tolerability of a fixed-dose combination of olmesartan and amlodipine in clinical practice
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چکیده
منابع مشابه
Effectiveness and tolerability of a fixed-dose combination of olmesartan and amlodipine in clinical practice
OBJECTIVES To assess the efficacy and tolerability of a fixed-dose combination of olmesartan and amlodipine in an unselected population of patients in primary care and to compare the results with recent randomized controlled trial evidence. METHODS A multicenter, noninterventional, noncontrolled observational study with 8241 hypertensive patients seen by 2187 physicians in daily practice. Blo...
متن کاملSafety and effectiveness of a fixed-dose combination of olmesartan, amlodipine, and hydrochlorothiazide in clinical practice
BACKGROUND Clinical trials indicate that the use of fixed-dose combinations (FDCs) is associated with a higher level of treatment adherence and prolonged blood pressure (BP) control. The aim of this study was to document the safety and effectiveness of the FDC olmesartan/amlodipine/hydrochlorothiazide in patients with essential hypertension in clinical practice. METHODS This multicenter, pros...
متن کاملEfficacy and tolerability between an olmesartan/amlodipine fixed-dose combination and an amlodipine double dose in mild to moderate hypertension.
Fixed-dose combinations (FDCs) are one of the options for improving blood pressure (BP) goal attainment. We enrolled 141 patients and evaluated the efficacy and safety between a fixed dose of olmesartan/amlodipine (OA) and a double dose of amlodipine (DA) for treating mild to moderate hypertension after amlodipine monotherapy failure. After at least 2 weeks of monotherapy failure, the patients ...
متن کاملDrug adherence to olmesartan/amlodipine fixed combination in an Italian clinical practice setting
OBJECTIVE To investigate the criteria for prescribing a combination pill for hypertensive patients, and whether the combination pill improves medication adherence. MATERIALS AND METHODS This was a retrospective cohort study, performed in three Italian local health units. We selected all adult subjects who received at least one prescription of antihypertensive drugs between September 1, 2011 a...
متن کاملCritical appraisal of amlodipine and olmesartan medoxomil fixed-dose combination in achieving blood pressure goals
Hypertension remains a significant health burden in the United States, with almost one in three adults affected, and is an independent risk factor for cardiovascular and renal disease. The goal of antihypertensive treatment is to reduce cardiovascular and renal morbidity and mortality by reducing blood pressure (BP). Guidelines recommend a target BP of <140/90 mmHg, with a more stringent goal o...
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ژورنال
عنوان ژورنال: Vascular Health and Risk Management
سال: 2010
ISSN: 1178-2048
DOI: 10.2147/vhrm.s13441